Vancomycin se yon antibyotik glikopeptid ki itilize pou anti-bakteri
Pwodwi detay
| Non | Vankomisin |
| Nimewo CAS | 1404-90-6 |
| Fòmil molekilè | C66H75Cl2N9O24 |
| Pwa molekilè | 1449.25 |
| Nimewo EINECS | 215-772-6 |
| Dansite | 1.2882 (estimasyon ki graj) |
| Endèks refraktif | 1.7350 (estimasyon) |
| Kondisyon depo | Sele nan sèk, 2-8 ° C |
Sinonim
Vancomycin(baz ak/oswa sèl ki pa espesifye);VANCOMYCIN;VancomycinBase;(3S,6R,7R,22R,23S,26S,36R,38aR)-3-(2-Amino-2-oxoethyl)-44-[[2-O-( 3-amino-2,3,6-trideoxy-3-C-methyl-α-L-lyxo-hexopyranosyl)-β-D-glucopyranosyl]oxy]-10,19-dikloro-2,3,4,5, 6,7,23,24,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-[[(2R)-4-methChemicalbookyl-2-(methylamino) )-1-oxopentyl]amino]-2,5,24,38,39-pentaoxo-22H-8,11:18,21-Dietheno-23,36-(iminomethano)-13,16:31,35-dimetheno -1H,16H-[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylicacid.
Deskripsyon
Vancomycin se yon antibyotik glikopeptid.Mekanis aksyon li yo se mare ak gwo afinite ak alanylalanine nan fen poli-tèminal peptide précurseur nan miray selil sansib bakteri, bloke sentèz peptidoglycan makromolekilè ki konstitye miray selil bakteri, sa ki lakòz destriksyon selil la. miray la touye bakteri.Vancomycin se efikas pou enfeksyon grav ki te koze pa bakteri Gram-pozitif, espesyalman sa yo ki te koze pa Staphylococcus aureus ki reziste methicillin, Staphylococcus epidermidis, ak Enterococcus ki rezistan ak lòt antibyotik oswa ki gen move efikasite.
Endikasyon
Li limite a sa sèlman enfeksyon sistemik ki te koze pa Staphylococcus aureus ki reziste methicillin (MRSA) ak enfeksyon entesten ak enfeksyon sistemik ki te koze pa Clostridium difficile;Pasyan ki gen alèji ak penisilin pa ka sèvi ak penisilin oswa sefalosporin nan pasyan ki gen enfeksyon grav stafilokok, oswa moun ki gen enfeksyon grav stafilokòk ki pa reponn ak antibyotik ki anwo yo, yo ka itilize vancomycin.Pwodui sa a tou itilize pou tretman andokardit Enterococcus ak endokardit Corynebacterium (tankou difteri) nan moun ki fè alèji ak penisilin.Tretman nan enfeksyon staphylococcus-induit arteriovenous shunt nan pasyan emodyaliz alèji ak penisilin ak ki pa alèji ak penisilin.
